Becoming a worm
Sequencing of the worm genome has allowed Hill et al. to design oligonucleotide arrays representing 18,791 (98%) of the predicted worm open reading frames (ORFs). In the 27 October Science, they report the use of these arrays to analyze transcripts from six developmentally staged worm populations from eggs to adults (Science 2000, 290:809-812). Only 56% of the ORFs are detected at least once, suggesting that others are missed because they are expressed at very low levels in specific tissues or u
Oct 30, 2000
Sequencing of the worm genome has allowed Hill