Bugs in flies
The mechanisms underlying the innate immune system are highly conserved from flies to mammals. In the December 18 Proceedings of the National Academy of Sciences, Phil Irving and colleagues describe a genome-wide screen for genes induced in Drosophila following infection with bacteria or fungi (Proc Natl Acad Sci USA 2001, 98:15119-15124).They performed oligonucleotide-array gene-profiling analysis on material from flies inoculated with Gram-negative or Gram-positive bacteria or with the fungi B
Dec 11, 2001
The mechanisms underlying the innate immune system are highly conserved from flies to mammals. In the December 18
They performed oligonucleotide-array gene-profiling analysis on material from flies inoculated with Gram-negative or Gram-positive bacteria or with the fungi
Nearly half of the immune-induced genes are of unknown...