cis-regulatory modules
Deciphering the regulatory codes that dictate developmental and tissue-specific patterns of transcriptional control is a formidable challenge. In the January 22 Proceedings of the National Academy of Sciences, Benjamin Berman and colleagues describe a computational approach to explore the grammar of cis-regulatory modules (Proc Natl Acad Sci USA 2002, 99:757-762).They focused on the Drosophila genome and searched for high, local densities of binding sites for multiple transcription factors (Bico
Jan 22, 2002
Deciphering the regulatory codes that dictate developmental and tissue-specific patterns of transcriptional control is a formidable challenge. In the January 22
They focused on the
An accompanying paper by Markstein