Cloned mice are obese
Cloning using somatic cells has potentially important clinical and therapeutic applications, but the long-term effects of cloning on the offspring of these animals remains unknown. In March Nature Medicine, Kellie Tamashiro and colleagues from University of Cincinnati College of Medicine, Ohio, USA, show that cloned mice have an obese phenotype, but that this is not transmitted to their offspring.Tamashiro et al. examined cloned mice of different background strains (B6C3F1, B6D2F1) and used spec
Feb 28, 2002
Cloning using somatic cells has potentially important clinical and therapeutic applications, but the long-term effects of cloning on the offspring of these animals remains unknown. In March
Tamashiro
These findings "provide further evidence that cloned embryos are vulnerable to epigenetic change" wrote Ian Wilmut from Roslin...