Controlling the bacterial cell cycle
In the 15 December Science, Laub et al. find that a full 19% of the genome of the bacterium Caulobacter crescentus is subject to cell-cycle-specific regulation (Science 2000, 290:2144-2148). A surprising number of genes are induced, as in yeast, just before they are needed. Other genes, such as those directing the construction of the flagella and pilus, are induced in transcriptional cascades, with the order of induction reflecting the order of assembly of the respective apparatus. Laub et al. a
Dec 17, 2000
In the 15 December