Corticotropin-releasing factor affinity switch
Corticotropin-releasing factor (CRF) is an early signal of the stress response and is also an important neuromodulator of memory consolidation, anxiety, locomotor activity and food intake. In September 25 Proceedings of the National Academy of Sciences, Klaus Eckart and colleagues from the Max Planck Institute of Experimental Medicine, Goettingen, show that it is possible to selectively change the binding properties of the CRF hormone by replacing a single amino acid in the CRF structure (Proc N
Oct 11, 2001
Corticotropin-releasing factor (CRF) is an early signal of the stress response and is also an important neuromodulator of memory consolidation, anxiety, locomotor activity and food intake. In September 25
Eckart