Cycling surprises
Array analysis of dividing cells has been tackled for yeast, but in the January Nature Genetics Cho et al. present the first large-scale analysis in human cells (Nat Genet 2001, 27:48-54). They identify 731 of 40,000 human genes and expressed sequence tags (ESTs) as being cell cycle regulated in primary fibroblasts, and use a functional classification system to identify coordinate regulation of pathways. Notable surprises include upregulation of motility-related genes in G2 (perhaps to prepare d
Jan 4, 2001
Array analysis of dividing cells has been tackled for yeast, but in the January
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