Cytokine may protect against Salmonella
Macrophage migration inhibitory factor is a pro-inflammatory cytokine that acts at the interface between the immune system and the hypothalamus –pituitary–adrenal stress axis, but its complete role in infectious diseases remains unclear. In September 23 Proceedings of the National Academies of Sciences, Heidrun Koebernick and colleagues at the Max Planck Institute for Infection Biology, Berlin, Germany, show that MIF plays a pivotal role in immunity against Salmonella typhimurium (PN
Sep 24, 2002
Macrophage migration inhibitory factor is a pro-inflammatory cytokine that acts at the interface between the immune system and the hypothalamus –pituitary–adrenal stress axis, but its complete role in infectious diseases remains unclear. In September 23
Koebernick et al. used MIF-/- knockout mice and observed that these animals could not control infections with wild-type