Drugging NKT cells
Drug loaded dendritic cells can induce a prolonged natural killer T cell response.
Aug 4, 2002
When injected intravenously into mice, the drug α-galactosylceramide (αGalCer) — originally isolated from molluscs —binds to CD1d, mediating a rapid natural killer T (NKT) lymphocyte reaction that triggers anti-tumor activity, but this response is short lived and non-specific. In August 5
Fujii