Dynein on the move
Electron microscopy studies further elucidate the dynamics of protein motor movement.
Feb 12, 2003
Dyneins are eukaryotic force-generating ATPases responsible for movement along microtubules, driving the beating of cilia and flagella, and key cytoplasmic processes, such as intracellular transport and mitosis. How these complex mechanoenzymes generate force has been unclear. In the February 13
Burgess et al. used a combination of electron microscopy and image processing to analyze the motions of dynein C — an isoform from the flagella of the alga