Exploiting the autoimmune response
Conjugation of a self-antigen to papillomavirus-like particles elicit high titers of autoantibodies that can be used to treat arthritis and other diseases.
Aug 13, 2001
Injection of monoclonal antibodies against key self-proteins produced encouraging results in diseases models such as arthritis, allergy and breast cancer. In August
Chackerian
Autoantibody-inducing vaccines based on conjugated VLPs can be highly immunogenic and are probably efficient in diseases for which monoclonal antibody-based therapies have been suggested. But, the safety of having long-term circulating self-reactive antibodies remains...