FLiP-ing insulators
Insulators define independent genomic regions that are protected from the influence of distant regulatory sequences. In the 1 November EMBO Journal, Parnell and Geyer describe a novel application of the FLP recombinase to investigate the properties of two Drosophila insulators, called gypsy and scs (EMBO J 2000, 19:5864-5874). Neither insulator affected FLP recombination and protein-protein interactions at adjacent recombination sites, suggesting that gypsy and scs do not act by general inhibiti
Nov 22, 2000
Insulators define independent genomic regions that are protected from the influence of distant regulatory sequences. In the 1 November