Gene Genie

SAGE Genie provides new tools for exploring human gene-expression data.

Jonathan Weitzman(

Finding out where and when a gene is expressed is often the first approach to discovering its physiological function. To help researchers follow expression patterns, the Cancer Genome Anatomy Project has established SAGEmap, a database of expression data from serial analysis of gene expression (SAGE) studies. In the Early Edition of the Proceedings of the National Academy of Sciences, Kathy Boon and colleagues report the creation of SAGE Genie, a set of bioinformatics tools that allow the user to navigate the mountains of gene expression-data (Proc Natl Acad Sci USA 2002, DOI:10.1073/pnas.152324199).

Boon et al. began with 6.8 million experimentally observed SAGE tags, which they processed into 105 databases according to different features. They also assessed the quality and reliability of each tag sequence, and created a list of 'confidence SAGE tags'. The 'SAGE Anatomic Viewer' offers a simple interface, showing the graphical representation of tissue-specific...

Interested in reading more?

Become a Member of

Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?