Gene therapy monkey business
New adeno-associated viruses isolated from monkeys may provide safe vectors for gene therapy.
Aug 20, 2002
Adeno-associated viruses (AAVs) belong to the
They aligned known primate and non-primate AAV genome sequences and selected conserved regions for amplification by PCR. This allowed them to isolate two new viruses, AAV7 and AAV8, from the DNA of rhesus monkey heart tissues. Gao
The low immunogenicity and favorable...