genotype influences chemotherapy results
Oxidative stress has been implicated in the metabolism of chemotherapy drugs. The mechanisms have been linked to the genes that encode glutathione S-transferase (GST) which are critical in protection against oxidative stress.In March Journal of Clinical Oncology Stella Davies and colleagues demonstrate that presence or absence of GST genes may influence the outcome of treatment for childhood acute myeloid leukaemia (AML).Davies et al genotyped the GST isoenzyme genes GSTT1 and GSTM1 in 306 child
Mar 8, 2001
Oxidative stress has been implicated in the metabolism of chemotherapy drugs. The mechanisms have been linked to the genes that encode glutathione S-transferase (GST) which are critical in protection against oxidative stress.
In March
Davies
If confirmed in further studies,