The ability to taste gives animals a means to assess the identity and quality of potential food substances. In an Advanced Online Publication from
They employed an expression screening strategy, expressing putative G-protein-coupled receptors in human cells and assaying for stimulus-induced changes in intracellular calcium. A combination of mouse T1R1 and T1R3 taste receptors generated an effective heteromeric receptor for the 20 standard L-amino acids, but not D-amino acids. Amino acids can represent both sweet and unami ('delicious') tastes.