Gut genomics
The human intestine is home to numerous populations of microorganisms, but we know little about how the gut microflora influence our physiology. As described in the February 2 Science, Hooper et al. took a genomics approach to investigate the affect of resident bacteria on host gene expression in the gut (Science 2001, 291:881-884). The authors infected germ-free mice with the common gut bacterium Bacteroides thetaiotaomicron and measured host transcriptional responses using microarray analysis.
Feb 5, 2001
The human intestine is home to numerous populations of microorganisms, but we know little about how the gut microflora influence our physiology. As described in the February 2