Healing with stem cells
Progressive heart failure and death can occur following myocardial infarction due to ventricular remodelling and fibrosis. Neoangiogenesis occurs normally within the infarcted tissue, but the new capillary network is unable to support the greater demands of the hypertrophied myocardium and remaining myocytes are unable to reconstitute the necrotic tissue.In the April Nature Medicine, Kocher and colleagues Columbia University, New York show that bone marrow from adult humans can be used to help n
Apr 1, 2001
Progressive heart failure and death can occur following myocardial infarction due to ventricular remodelling and fibrosis. Neoangiogenesis occurs normally within the infarcted tissue, but the new capillary network is unable to support the greater demands of the hypertrophied myocardium and remaining myocytes are unable to reconstitute the necrotic tissue.
In the April
They used selected bone marrow cells from human donors and athymic rat recipients with ligation-induced coronary thrombosis as an experimental model of infarction. Kocher