HIV favors active genes
HIV-1 chooses active genes and local hotspots for integration in the human genome.
Aug 27, 2002
HIV replication requires integration of the proviral cDNA into human DNA at specific chromosomal sites, but the mechanism for selecting these sites has been poorly understood. In August 23
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"The findings may have implications for developing more effective gene therapies", says Frederic Bushman, senior author of the paper. "For example, data...