Keeping a CHEK on breast cancer
Mutations in the tumor suppressor genes BRCA1 and BRCA2 account for a small percentage of breast cancer cases. In 22 April Advanced Online Publication from Nature Genetics, Meijers-Heijboer and colleagues from the CHEK-Breast Cancer Consortium report the identification of a mutation in the CHEK2 gene that increases the risk of breast cancer in both women and men (Nat Genet 2002, DOI: 10.1038/ng879).They performed a genome-wide linkage search in a family with BRCA-independent breast cancer and id
Apr 23, 2002
Mutations in the tumor suppressor genes BRCA1 and BRCA2 account for a small percentage of breast cancer cases. In 22 April Advanced Online Publication from
They performed a genome-wide linkage search in a family with