Link between HF1 and AMD grows
Pursuit of genetic factors involved in a leading cause of blindness points to complement pathway
May 1, 2005
For the fourth time, variants of the complement Factor H gene (HF1/CFH) have been linked to the likelihood of developing age-related macular degeneration (AMD), researchers report in the early edition of
This latest link comes on the heels of three independent reports that connected HF1 to AMD, all of which appeared together in
"Gregory Hageman had a theory that inflammation was involved in AMD, but nobody really believed him, including me," said Rando Allikmets, from Columbia University and senior author of the