Long-term risks of chemotherapy
Chemotherapy can generate new cancerous growths and may carry significant cardiovascular risks.
Feb 26, 2002
Current treatment regimes for many cancers are so successful that patients are surviving for much longer than initially envisaged. This presents a unique set of problems as the mutagenic effects of their chemotherapy can lead to the long-term development of a second malignancy, but the molecular interactions underlying these observations remain unclear. In February
Amplification of drug-selected genes in rodent cells is driven by recurrent breaks within chromosomal common fragile sites (CFSs), via the breakage-fusion-bridge (BFB) mechanism. Hellman