Making sense of antisense
The yeast Candida albicans is the major pathogen causing human fungal infections. C. albicans is not amenable to functional genomic strategies used for other micro-organisms, because of mating difficulties, its diploid nature and the lack of random insertional mutagenesis methods.In March Nature Biotechnology Marianne De Backer and colleagues describe an approach to overcoming these limitations, in order to perform a genome-wide screen for gene function (Nature Biotechnology 2001, 19:235-241). T
Mar 7, 2001
The yeast
In March
De Backer