Maternal tolerance
Corticotrophin-releasing hormone (CRH) participates in the implantation of embryos and early pregnancy tolerance via pathways that remain poorly understood. In October Nature Immunology, Makrigiannakis and colleagues from University of Crete School of Medicine, Greece, show that locally produced embryonic and endometrial CRH promotes implantation and maintenance of early pregnancy primarily by killing activated T cells.Makrigiannakis et al. studied isolated primary human extravillous trophoblast
Oct 9, 2001
Corticotrophin-releasing hormone (CRH) participates in the implantation of embryos and early pregnancy tolerance via pathways that remain poorly understood. In October
Makrigiannakis
These results suggest a potential cause of female infertility and may also lead to the...