MicroRNAs
Large families of RNA molecules of 21-22 nucleotides, called microRNAs, have been found in a number of species. In an Advanced Online Publication from Nature Genetics, Eric Lai from the University of California at Berkeley, describes a family of microRNAs in Drosophila (Nat Genet 2002, DOI:10.1038/ng865).He found that 11 Drosophila microRNAs are complementary to the K-box motif (cUGUGAUa), Brd box (AGCUUUA) and GY box (uGUCUUCC) motifs present in the 3' untranslated regions (UTRs) of several bas
Mar 27, 2002
Large families of RNA molecules of 21-22 nucleotides, called microRNAs, have been found in a number of species. In an Advanced Online Publication from
He found that 11
The conservation of some microRNAs in man and worms will prompt work on defining a regulatory role for microRNA-3'UTR RNA duplexes.