Molecular effects of the fat hormone
Adipose-derived protein Acrp30 is a recently identified hormone released from fat tissue that has a role in glucose metabolism, but its molecular effects remain elusive. In December 15 Journal of Clinical Investigation, Terry Combs and colleagues from Albert Einstein College of Medicine, Bronx, New York, show that a moderate rise in circulating levels of Acrp30 inhibits both the expression of hepatic gluconeogenic enzymes and the rate of endogenous glucose production. Combs et al. studied the ef
Dec 19, 2001
Adipose-derived protein Acrp30 is a recently identified hormone released from fat tissue that has a role in glucose metabolism, but its molecular effects remain elusive. In December 15
Combs
The authors...