Mother nurture
Genomic imprinting is characterized by epigenetic regulation of mRNA expression from a single parental allele. The two parental alleles of imprinted genes are differentially methylated. The mouse gene Peg3 is imprinted and has been shown to control the maternal nurturing of newborn pups in mice. In the January Genomics, Murphy et al. show that the human homolog of Peg3 is also imprinted (Genomics 2001, 71:110-117). They identified a CpG island (CpG islands are much more frequent around imprinted
Jan 24, 2001
Genomic imprinting is characterized by epigenetic regulation of mRNA expression from a single parental allele. The two parental alleles of imprinted genes are differentially methylated. The mouse gene