New lipid-lowering drugs
Drugs such as statins can reduce high plasma levels of the low-density lipoprotein (LDL) cholesterol that is a significant risk factor for atherosclerosis. In December Nature Medicine Thierry Grand-Perret and colleagues from GlaxoSmithKline, France showed that compounds that bind directly to the sterol regulating protein SCAP, could lower cholesterol levels via a mechanism other than that employed by the statins.Grand-Perret et al. administered SCAP ligands to hyperlipidemic hamsters and found t
Dec 2, 2001
Drugs such as statins can reduce high plasma levels of the low-density lipoprotein (LDL) cholesterol that is a significant risk factor for atherosclerosis. In December
Grand-Perret
"Further elucidation of the molecular pathways that...