Optical coherence tomography generates high-resolution images of tissue
Patients with chronic gastroesophageal reflux disease can develop specialised intestinal metaplasia (SIM). This is a histological lesion that predisposes to adenocarcinoma of the oesophagus, and is currently diagnosed by endoscopy and biopsy. In the January Gastroenterology a team from Harvard Medical School suggest that a new method, optical coherence tomography (OCT), is a more reliable and sensitive technique for diagnosing SIM.
OCT can produce high-resolution (~10 μm) cross-sectional images of tissue
John M. Poneros and colleagues studied 121 patients, acquiring a total of 288 biopsies that they then correlated with OCT...