Parkinson's disease triggers
-synuclein in complex with 14-3-3 chaperones may be responsible for the nerve destruction in Parkinson's disease.
Jun 5, 2002
Parkinson's disease (PD) is caused by a progressive deterioration of the neurons that control movement and contain dopamine, but the mechanism by which dopaminergic neurons are selectively lost has been unclear. In June
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In addition, they found that soluble protein complexes that contain α-synuclein and 14-3-3 protein chaperones, mediate dopamine-dependent neurotoxicity in PD.
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