Potassium ions mediate bacterial destruction
The most important mechanism by which neutrophils inactivate bacteria was thought to be mediated by reactive oxygen species and myeloperoxidase-catalysed halogenation. But in March 21 Nature, Emer Reeves and colleagues from University College London show that the killing activity of neutrophils works through activation of proteases by potassium ions (Nature 2002, 416:291-297).Reeves et al. found that mice made deficient in neutrophil-granule proteases but with normal superoxide production and io
Mar 24, 2002
The most important mechanism by which neutrophils inactivate bacteria was thought to be mediated by reactive oxygen species and myeloperoxidase-catalysed halogenation. But in March 21
Reeves