Prion detection in peripheral tissues
A firm diagnosis of variant Creutzfeldt Jakob disease (vCJD) is difficult to make because it is based on distinguishing misfolded prion proteins (PrPSc) from normally folded prion proteins in human brain biopsies. In 20 July issue of the Lancet, Wadsworth and colleagues from Imperial College School of Medicine, London, UK, describe a new technique based on a highly sensitive immunoblotting assay that can accurately detect PrPSc in peripheral tissue in patients suspected of vCJD. Wadsworth et al.
Jul 19, 2001
A firm diagnosis of variant Creutzfeldt Jakob disease (vCJD) is difficult to make because it is based on distinguishing misfolded prion proteins (PrPSc) from normally folded prion proteins in human brain biopsies. In 20 July issue of the
Wadsworth