Redox controls HIV entry
The redox state of the thiols in domain 2 of CD4 controls entry of HIV-1 into susceptible cells.
Jul 2, 2002
CD4 mediates immune cell-cell interactions and is required for HIV to enter cells, but the precise nature of the molecular interactions involved has been unclear. In July 1 advanced online
Matthias
"Perturbation of this redox event may be a...