Refining the genome
Genome revised down to under 25,000 genes; failings of whole genome shotgun revealed
Oct 20, 2004
A comparison of human genome sequences produced using different approaches by the International Human Genome Sequencing Consortium and the private firm Celera reveals that whole genome shotgun sequencing (WGS), as used by Celera, fails miserably on genome segmental duplications.
Writing in
For the current study, Eichler teamed up with previous collaborators Granger G. Sutton and Aaron L. Halpern, both now at the J. Craig Venter Institute in Rockville, Md., in an apparent revisiting of results published by