Screening for genes that control the wiring of the nervous system
In 20 March Current Biology, Kai Zinn and colleagues at the California Institute of Technology, describe a genetic screen for identifying genes involved in axon guidance and synapse formation (Curr Biol 2001, 11:417-430).They started with a set of 2293 Drosophila lines, each carrying an 'EP element' inserted at known sites throughout the genome. An EP element is a transposable P element containing a basal promoter and 14 copies of the yeast UAS sequence, which responds to the transcription facto
Mar 26, 2001
In 20 March
They started with a set of 2293
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