Second-generation microarrays
Current microarray analysis uses 'chips' containing either 25-residue oligonucleotides synthesized by photolithography or cDNAs placed by robotic spotting. In the April Nature Biotechnology, Hughes et al. describe a microarray technique that exploits an ink-jet printing method and standard phosphoramidite chemistry (Nature Biotechnology 2001, 19:342-347). The ink-jet synthesizer can deliver 25,000 phosphoramidite-containing microdroplets to a 25 x 75 mm glass slide. Hughes et al. examined a larg
Apr 10, 2001
Current microarray analysis uses 'chips' containing either 25-residue oligonucleotides synthesized by photolithography or cDNAs placed by robotic spotting. In the April