The rate, orientation and direction of cell growth and division determine the shape that a given tissue will adopt. In the March 13
Measurements of the spatiotemporal changes in cell proliferation and anisotropy (the preferential direction of growth) were combined with computational modeling. They found that the direction of growth rather than regional differences in growth rate (cell doubling time) dictated petal asymmetry.
In an accompanying review, Claude Desplan and Thomas Lecuit draw striking parallels with analysis of wing formation in