Shear stress
The vascular endothelium is remarkably versatile in its ability to respond to both soluble chemical stimuli and mechanical stimuli. In the April 10 Proceedings of the National Academy of Sciences, Garcia-Cardena et al. report the results of a high-throughput genome-wide analysis of gene modulation by biomechanical activation (Proc Natl Acad Sci USA 2001, 98:4478-4485). They used cDNA arrays to examine the effects of biomechnical forces on gene expression in cultured monolayers of human umbilical
Apr 16, 2001
The vascular endothelium is remarkably versatile in its ability to respond to both soluble chemical stimuli and mechanical stimuli. In the April 10