Signals for malaria infection
coupled receptor signals may control malarial infection
Sep 18, 2003
Harrison et al. examined cocultures of parasites and erythrocytic peptides and observed that agonists that stimulate cyclic adenosine 3',5'-monophosphate production caused an increase in malarial infection that could be blocked by specific receptor antagonists. In addition, the authors showed that peptides designed to inhibit Gαs protein function reduced parasitemia in