Single amino acid can change progression to AIDS
A single amino acid change in HLA molecules can have a substantial effect on the rate of progression to AIDS in patients infected with HIV-1.
Jun 4, 2001
The strongest susceptibility to progression from human immunodeficiency virus type 1 (HIV-1) infection to the acquired immunodeficiency syndrome (AIDS) is conferred by the major-histocompatibility-complex (MHC) class I type HLA-B*35,Cw*04 allele. In May 31
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