Somatic hypermutation
Experiments in fibroblasts have identified an enzyme that induces hypermutation resembling the hypermutator of immunoglobulin genes in lymphocytes.
Jun 17, 2002
Somatic hypermutation, gene conversion and class-switch recombination are genetic rearrangements that generate the molecular diversity of immunoglobulin genes underlying the human immune system. In the 14 June
To examine hypermutation, Yoshikawa
They found large numbers of mutations in the