ssDNA Tools
Single-stranded oligonucleotides may provide a new tool for homologous recombination and genome modification.
May 31, 2001
Homologous recombination of DNA is a powerful tool for chromosome engineering experiments, but is a rare event, requiring long stretches of homology and complex reactions. Phage-mediated systems allow efficient recombination of linear DNA with relatively short homologies. In the June 5