Suicide gene therapy for colon cancer
Injection of suicide gene modified tumor cells induces a systemic antitumor response in a rat model of metastatic colon carcinoma.
Feb 13, 2002
Suicide gene therapy consists of introduction into tumor cells of a non-mammalian gene encoding an enzyme (such as cytosine deaminase) that converts a non-toxic prodrug (5-fluorocytosine) into a lethal one (5-fluorouracil). In February
Pierrefite-Carle
These data suggests that suicide gene therapy in this form "could represent a powerful alternative therapeutic regimen for...