Telomeres and Fanconi's anemia
Telomere breakage and replicative shortening account for telomere shortening in Fanconi 's anemia.
Feb 28, 2002
Fanconi's anemia (FA) is a genetic disease characterized by increased chromosome instability associated with congenital malformations, progressive pancytopenia and increased susceptibility to cancer. FA lymphocytes have an accelerated shortening of telomeres, but the molecular mechanisms involved are unclear. In February
Callén
These results give new insights into the mechanisms and biological...