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Calcium has long been known to be important in sperm function, but a full understanding of the molecular mechanisms of its action has remained elusive. In October 11 Nature, Dejian Ren and colleagues from Howard Hughes Medical Institute and Harvard Medical School describe a new cation channel, CatSper, which is vital to cAMP-mediated Ca2+ influx in sperm, sperm motility and fertilization.Ren et al. analyzed DNA for sequences that might code for known voltage-gated calcium channels and found a ge
Oct 10, 2001
Calcium has long been known to be important in sperm function, but a full understanding of the molecular mechanisms of its action has remained elusive. In October 11
Ren