Where is the proteome?
Where a protein is found in a cell can reveal a lot about its function. In the March 15 Genes and Development, Kumar and colleagues report the subcellular localization of 2,744 proteins in the budding yeast, Saccharomyces cerevisiae.Kumar et al. tagged the proteins with an easy-to-detect epitope, mostly using direct cloning but for some using random transposon mutagenesis, and examined the subcellular localization of the tagged proteins using immunofluorescence. Together with previously publishe
Mar 17, 2002
Where a protein is found in a cell can reveal a lot about its function. In the March 15
Kumar
Extrapolating their results to...