Yeasts: the basis for new vaccines
mediated response and protective immunity in mice.
May 1, 2001
Efficient cell-mediated immunity requires the activation of dendritic cells (DC). Currently there is a great deal of interest in vaccine strategies that employ DC immunostimulatory complexes. In May
Stubbs
Yeast also exerted a strong adjuvant effect, augmenting DC presentation of the exogenous whole-protein antigen to MHC class I- and class II-restricted T cells. This suggests that recombinant yeast may be a good...