Zooming in on micrometastases
Researchers have developed an optimized procedure for analyzing the genome and transcriptome of single tumour cells.
Apr 9, 2002
Micrometastases of disseminated tumour cells present a threat to the long-term survival of cancer patients. Analysis of these rare, lone disseminated cells requires an amplification procedure. In the April
Klein
They were able to detect several genes implicated in cell-cycle regulation, cytoskeletal organization and cell adhesion or motility. Among these they found high expression of