“Where do you see the most important or interesting progress occurring in immunology over the next few years.” That was the question recently put to some two dozen senior immunologists by the editorial staff of the Institute for Scientific Information’s Atlas of Science: Immunology. The scientists surveyed—a distinguished, international group that represents academia, independent laboratories, and industry—serve as the editorial advisory board of the journal.
In general, these 24 scientists highlighted select areas that show good prospects for significant advances, such as the study of lymphokines and biological response modifers, T-cells, and auto-immunity. Here’s where the experts predict significant developments.
Lymphokine structure and function relationships. leading through x-ray crystallography to rational drug design.
Structure of peptide and protein mediators involved in immuno-regulation and design of molecules that mimic their activity.
Mapping precisely antigenic sites and upregulation of immune response against viruses and tumor antigens.
Cellular and molecular basis for T-cell...