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Simon Silver

The Scientist has asked a group of experts to comment periodically upon recent articles that they have found noteworthy. Their selections, presented herein every issue, are neither endorsements of content nor the result of systematic searching. Rather, the list represents personal choices of articles the columnists believe the scientific community as a whole may also find interesting. Reprints of any articles cited here may be ordered through The Genuine Article, 3501 Market St., Philadelphia, Pa. 19104, or by telephoning (215) 386-4399.


Author: SIMON SILVER
Department of Microbiology & Immunology
University of Illinois
Chicago

  • Telomeres "tell" chromosomes where to end and prevent loss of chromosome tips. They may also be involved in chromosomal association during mitosis and meiosis. The formation dimers of telomere hairpin structures have been demonstrated through the use of synthetic telomere DNA oligonucleotides in vitro. The synthetic structure used consists of four guanine residues, hydrogen-bonded in a circular...

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